Our research group dug deep into the endoplasmic reticulum stress (ER stress) and associated proteins in search of pathological relevancy which help to develop medicines. Our research focus is on integrated approach, where basic and preclinical investigations are integrated for breakthrough in the development of medicines. We have multinational team dedicated to define the molecular mechanism of ER stress-originated pathologies in cancer, diabetes and obesity. To accomplish the wider goals of the laboratory, we employ multi-disciplinary approach, where ER physiology, biochemistry, molecular biology are adopted along with the in vivo and in vitro experiments to identify key molecular pathways that determine the cell’s response to physiologic and pathophysiologic ER stress. Our researches are supported by various national and international organizations.